Immediate and long term improving pain relief*. Penetrates deeply. Relieves back, knee, neck and shoulder pain. With glucosamine & chondroitin sulfate for skin conditioning. Exclusive Fus Me skin delivery system. *With continued use. The eight-week clinical trial, published in the Journal of Rheumatology, involved 63 patients who had suffered from chronic osteoarthritis knee pain for an average of 10 years.